Dual Bronchodilator Therapy as First-Line Treatment in Maintenance-Naïve Patients with Symptomatic COPD: A Pre-Specified Analysis of the EMAX Trial.

Bjermer Leif Isabelle H Boucot Francois Maltais Edward M KerwinIan P NayaLee TombsPaul W JonesChris ComptonDavid A LipsonClaus F Vogelmeier

Published in: International journal of chronic obstructive pulmonary disease (2021)

Similar to maintenance-treated patients, maintenance-naïve patients receiving umeclidinium/vilanterol showed greater improvements in lung function and symptoms compared with patients receiving umeclidinium or salmeterol. These findings provide support for the consideration of dual bronchodilator treatment in symptomatic maintenance-naïve patients with COPD.

Keyphrases

lung function
chronic obstructive pulmonary disease
cystic fibrosis
air pollution
end stage renal disease
newly diagnosed
chronic kidney disease
peritoneal dialysis
clinical trial
randomized controlled trial
phase iii
physical activity
patient reported outcomes
sleep quality
bone marrow