GPER Stimulation Attenuates Cardiac Dysfunction in a Rat Model of Preeclampsia.

Allan Kardec Nogueira de AlencarKenneth F SwanSmruti MahapatraSarah H LindseyGabriella C PridjianCarolyn L Bayer

Published in: Hypertension (Dallas, Tex. : 1979) (2024)

The therapeutic intervention of G-1 significantly mitigated the cardiovascular dysfunction observed in the RUPP rat model of preeclampsia. This discovery underscores the broader significance of understanding GPER's role in the context of preeclampsia-related cardiovascular complications.

Keyphrases

early onset
estrogen receptor
pregnancy outcomes
oxidative stress
randomized controlled trial
small molecule
left ventricular
risk factors
high throughput
pregnant women
single cell
drug induced