Four novel polymorphisms in long non-coding RNA HOTTIP are associated with the risk and prognosis of colorectal cancer.

Zhi LvQian XuLiping SunJing WenXinxin FangChengzhong XingYuan Yuan

Published in: Bioscience reports (2019)

These findings suggest HOTTIP SNPs could potentially be predictive biomarkers for CRC risk and prognosis. The present study provides clues for further exploration of novel lncRNA-based genetic biomarkers to predict CRC susceptibility as well as clinical outcome.

Keyphrases

long non coding rna
poor prognosis
genome wide
gene expression
copy number