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Nail as a Window to Diagnosing Multisystem Langerhans Cell Histiocytosis: A Case Report and Review of Literature.

Arun SomasundaramSenthil Kumar PeriyasamyNarayanan ArunachalamTirekha Suyamprakasam VimalaSree Rekha JinkalaGunasekaran DhandapanySivaranjini Ramassamy
Published in: The American Journal of dermatopathology (2024)
Nail involvement in Langerhans cell histiocytosis is rarely reported in the literature. According to the reported cases, it is believed that the involvement of nails has a poor prognosis because of multisystem involvement. Performing a nail bed biopsy might be challenging for children. We report a child in whom nail bed biopsy served as the sole clue to the diagnosis of Langerhans cell histiocytosis in absentia of skin clue on a background of advanced multisystem involvement.
Keyphrases
  • poor prognosis
  • single cell
  • cell therapy
  • long non coding rna
  • systematic review
  • young adults
  • stem cells
  • ultrasound guided
  • mesenchymal stem cells