Gynostemma pentaphyllum extract and Gypenoside L enhance skeletal muscle differentiation and mitochondrial metabolism by activating the PGC-1α pathway in C2C12 myotubes.
Yoon Hee KimJae In JungYoung Eun JeonSo Mi KimTae Kyu OhJaesun LeeJoo-Myung MoonTae Young KimEun-Ji KimPublished in: Nutrition research and practice (2021)
The results indicated that GPE and GL enhance exercise performance by promoting myotube differentiation and mitochondrial metabolism through the upregulation of PGC-1α in C2C12 skeletal muscle.