Eribulin activity in soft tissue sarcoma monolayer and three-dimensional cell line models: could the combination with other drugs improve its antitumoral effect?
Javier EscuderoVictoria Heredia-SotoYinyin WangPatricia RuizYingying HuAlejandro GallegoJose Juan Pozo-KreilingerVirginia Martinez-MarinAlberto BerjonEduardo Ortiz-CruzDaniel BernabeuJaime FeliuJing TangAndres RedondoMarta MendiolaPublished in: Cancer cell international (2021)
Our results support the effect of eribulin on LPS, LMS and FS cell line models. The combination of eribulin with ifosfamide or pazopanib has shown in vitro synergy, which warrants further clinical research.