Eribulin activity in soft tissue sarcoma monolayer and three-dimensional cell line models: could the combination with other drugs improve its antitumoral effect?

Javier EscuderoVictoria Heredia-SotoYinyin WangPatricia RuizYingying HuAlejandro GallegoJose Juan Pozo-KreilingerVirginia Martinez-MarinAlberto BerjonEduardo Ortiz-CruzDaniel BernabeuJaime FeliuJing TangAndres RedondoMarta Mendiola

Published in: Cancer cell international (2021)

Our results support the effect of eribulin on LPS, LMS and FS cell line models. The combination of eribulin with ifosfamide or pazopanib has shown in vitro synergy, which warrants further clinical research.

Keyphrases

metastatic breast cancer
phase ii
inflammatory response
clinical trial
open label
anti inflammatory
randomized controlled trial
study protocol
metastatic renal cell carcinoma