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Associations of cerebrospinal fluid amyloidogenic nanoplaques with cytokines in Alzheimer's disease.

Mari AksnesHans Christian D AassAnn TiimanTrine Holt EdwinLars TereniusNenad BogdanovićVladana VukojevićAnne-Brita Knapskog
Published in: Translational neurodegeneration (2021)
The cytokine levels were not associated with amyloid status in this cohort. The nanoplaque levels were negatively associated with MIP-1β, MIP-1α and IL-8, which is in line with recent findings suggesting that the upregulation of some cytokine markers has a protective role and is negatively associated with AD progression.
Keyphrases
  • cerebrospinal fluid
  • cell proliferation
  • poor prognosis
  • cognitive decline
  • signaling pathway