Associations of cerebrospinal fluid amyloidogenic nanoplaques with cytokines in Alzheimer's disease.
Mari AksnesHans Christian D AassAnn TiimanTrine Holt EdwinLars TereniusNenad BogdanovićVladana VukojevićAnne-Brita KnapskogPublished in: Translational neurodegeneration (2021)
The cytokine levels were not associated with amyloid status in this cohort. The nanoplaque levels were negatively associated with MIP-1β, MIP-1α and IL-8, which is in line with recent findings suggesting that the upregulation of some cytokine markers has a protective role and is negatively associated with AD progression.