Intermittent noninvasive ventilation after extubation in patients with chronic respiratory disorders: a multicenter randomized controlled trial (VHYPER).

Frédéric VargasMarc ClavelPascale Sanchez-VerlanSylvain GarnierAlexandre BoyerHoang-Nam BuiBenjamin ClouzeauCharline SazioAissa KerchacheOlivier GuissetAntoine BenardJulien AsselineauBernard GaucheDidier GrusonStein SilvaPhilippe VignonGilles Hilbert

Published in: Intensive care medicine (2017)

Early NIV performed following a sequential protocol for the first 48 h after extubation decreased the risk of respiratory failure in patients with chronic respiratory disorders. Reintubation and mortality did not differ between NIV and conventional oxygen therapy.

Keyphrases

respiratory failure
randomized controlled trial
mechanical ventilation
extracorporeal membrane oxygenation
study protocol
acute respiratory distress syndrome
intensive care unit
respiratory tract
systematic review
high intensity
clinical trial
cardiac surgery
type diabetes
stem cells