Evaluating the clinical effectiveness of new beta-lactam/beta-lactamase inhibitor combination antibiotics: A systematic literature review and meta-analysis.

Geneva M Wilson Margaret A FitzpatrickKyle WaldingBeverly GonzalezMarin L SchweizerKatie J SudaCharlesnika T Evans

Published in: Antimicrobial stewardship & healthcare epidemiology : ASHE (2021)

C/T, C/A, I/R, and M/V are not inferior to standard therapies for treating various complicated infections, but they may have greater clinical success for treating MDRPA and CRE infections. More studies that evaluate the use of these antibiotics for drug-resistant infections are needed to determine their effectiveness.

Keyphrases

drug resistant
multidrug resistant
randomized controlled trial
systematic review
acinetobacter baumannii
gram negative
escherichia coli
klebsiella pneumoniae