The Effectiveness of Lifestyle Interventions in Heart Failure With Preserved Ejection Fraction: A Systematic Review and Network Meta-Analysis.
Grace W M WaltersJian L YeoJoanna M BilakCoral PepperGaurav S GulsinSuzanne C FreemanLaura J GrayGerry P McCANNEmer M BradyPublished in: Journal of cardiac failure (2024)
This network meta-analysis indicates that HIIT is the most effective lifestyle intervention studied to improve exercise capacity and QoL, with mean improvements exceeding the minimum clinically meaningful thresholds. HIIT is likely to be an underused management strategy in HFpEF, but further studies are needed to confirm long-term improvements in symptoms and clinical outcomes.