Involvement of GPR43 Receptor in Effect of Lacticaseibacillus rhamnosus on Murine Steroid Resistant Chronic Obstructive Pulmonary Disease: Relevance to Pro-Inflammatory Mediators and Oxidative Stress in Human Macrophages.

Ana Karolina Sá Fabiana Olímpio Jéssica Aparecida Vasconcelos Paloma Cristina Rosa Hugo Caire Faria Neto Carlos Rocha Oliveira Maurício Frota Camacho Uilla Barcick André Zelanis Flávio Aimbire

Published in: Nutrients (2024)

Lr attenuates lung inflammation and oxidative stress in COPD mice, suggesting the presence of a GPR43 receptor-dependent mechanism also found in macrophages.

Keyphrases

oxidative stress
chronic obstructive pulmonary disease
lung function
dna damage
ischemia reperfusion injury
diabetic rats
endothelial cells
induced apoptosis
fatty acid
induced pluripotent stem cells
binding protein
type diabetes
heat shock
cystic fibrosis
high fat diet induced
signaling pathway