Influence of conditioned medium from squamous cell carcinoma of the tongue on lymphoblasts and peripheral blood mononuclear cells.
Sofia Bevilaqua de CastroLucyene MiguitaMaria Fernanda Setúbal Destro RodriguesEmília Maria Gomes AguiarJuliana Mota SiqueiraNataly Harumi de Morais TakanoMarcos Custódio Neto da SilvaKristianne Porta Santos FernandesAna Paula Ligeiro de OliveiraFabio Daumas NunesPublished in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2022)
Collectively, our results suggest that the products derived from squamous cell carcinoma on inflammatory cells can promote an immunosuppressed environment by reducing cell viability, changing cytokine expression, and altering the cell immunoprofile.