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Long-term effectiveness and acceptability of switching from intravenous to subcutaneous infliximab in patients with inflammatory bowel disease treated with intensified doses: The REMSWITCH-LT study.

Anthony BuissonM NachuryM BazogeC YzetP WilsM DodelD CobanB PereiraMathurin Fumery
Published in: Alimentary pharmacology & therapeutics (2023)
Switching from IV to SC infliximab 120 mg every other week is safe and well accepted leading to low long-term risk of relapse. Tight monitoring and dose escalation should be recommended for patients receiving 10 mg/kg/6 weeks and 4 weeks, respectively.
Keyphrases
  • patients with inflammatory bowel disease
  • randomized controlled trial
  • ulcerative colitis
  • gestational age
  • systematic review
  • blood brain barrier
  • high dose
  • open label
  • free survival