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Tolerability and beneficial effects of sacubitril/valsartan on systemic right ventricular failure.

Marieke NederendPhilippine KièsMadelien V RegeerHubert W VliegenBart Ja MertensDaniëlle Robbers-VisserBerto Jorrit BoumaLaurens F TopsMartin J SchalijMonique R M JongbloedAnastasia D Egorova
Published in: Heart (British Cardiac Society) (2023)
Treatment with sacubitril/valsartan was associated with a low rate of adverse effects in this adult sRV cohort. Persisting improvement in 6-minute walking test distance, NT-proBNP levels and echocardiographic parameters of sRV function was observed in an on-treatment analysis and showed no differential response based on sex or anatomy.
Keyphrases
  • ejection fraction
  • clinical trial
  • randomized controlled trial
  • left atrial
  • combination therapy