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Belatacept conversion in an HIV-positive kidney transplant recipient following anti-thymocyte globulin induction.

Samantha A KutenSamir J PatelAshvin BaruA Osama GaberRustin D CrutchleyVenkataraman RamanathanRichard J Knight
Published in: Transplant infectious disease : an official journal of the Transplantation Society (2017)
Herein, we describe a case of early belatacept conversion in a human immunodeficiency virus (HIV)-positive kidney transplant recipient in an effort to improve suboptimal graft function and avoid drug interactions following anti-thymocyte globulin (ATG) administration. We observed improvement in renal function without HIV disease progression or opportunistic infections. Donor-specific antibodies appeared shortly after conversion but cleared without intervention. This case highlights belatacept as a means to improve renal function and avoid significant drug interactions even following ATG induction.
Keyphrases
  • hiv positive
  • human immunodeficiency virus
  • antiretroviral therapy
  • hiv infected
  • men who have sex with men
  • hiv aids
  • south africa
  • hepatitis c virus
  • hiv testing
  • randomized controlled trial