Belatacept conversion in an HIV-positive kidney transplant recipient following anti-thymocyte globulin induction.
Samantha A KutenSamir J PatelAshvin BaruA Osama GaberRustin D CrutchleyVenkataraman RamanathanRichard J KnightPublished in: Transplant infectious disease : an official journal of the Transplantation Society (2017)
Herein, we describe a case of early belatacept conversion in a human immunodeficiency virus (HIV)-positive kidney transplant recipient in an effort to improve suboptimal graft function and avoid drug interactions following anti-thymocyte globulin (ATG) administration. We observed improvement in renal function without HIV disease progression or opportunistic infections. Donor-specific antibodies appeared shortly after conversion but cleared without intervention. This case highlights belatacept as a means to improve renal function and avoid significant drug interactions even following ATG induction.