Pan-Cancer HLA Gene-Mediated Tumor Immunogenicity and Immune Evasion.

Published in: Molecular cancer research : MCR (2022)

Taken together, we highlight the prognostic potential of HLA genes in immunotherapies and suggest that higher tumor immunogenicity mediated by HLA expression may sometimes lead to tumor escape under strong selective pressure.

Keyphrases

genome wide
poor prognosis
squamous cell carcinoma
gene expression
transcription factor
dna methylation
childhood cancer