Investigating sex-specific associations of lipid traits with type 2 diabetes, glycemic traits and sex hormones using Mendelian randomization.

Published in: Cardiovascular diabetology (2023)

Lipid traits potentially relevant to CVD aetiology do not exhibit contrasting associations with CVD and type 2 diabetes. However, higher TG is associated with higher type 2 diabetes risk and glycemic traits, which in turn further increases TG specifically in women, possibly driven by sex hormones.

Keyphrases

type diabetes
genome wide
glycemic control
cardiovascular disease
insulin resistance
polycystic ovary syndrome
fatty acid
adipose tissue
pregnant women
sensitive detection
fluorescent probe
cervical cancer screening