Elevated expression of IL-17RB and ST2 on myeloid dendritic cells is associated with a Th2-skewed eosinophilic inflammation in nasal polyps.

Rui ZhengDan WangKai WangWen-Xiang GaoQin-Tai YangLi-Jie JiangMin ZhouYu-Jie CaoJianbo ShiYue-Qi Sun

Published in: Clinical and translational allergy (2018)

Increased expressions of IL-17RB and ST2 on mDCs are associated with enhanced local Th2 inflammation in NP, suggesting that mDCs might play a role in IL-25- and IL-33-induced type 2 responses and eosinophilic inflammation in NP.

Keyphrases

dendritic cells
chronic rhinosinusitis
oxidative stress
poor prognosis
immune response
diabetic rats
bone marrow
high glucose
endothelial cells
long non coding rna
binding protein