MeCP2 epigenetically regulates alpha-smooth muscle actin in human lung fibroblasts.

Zheyi XiangQingxian ZhouMin HuYan Y Sanders

Published in: Journal of cellular biochemistry (2020)

Our data indicate that the methyl-binding protein MeCP2 is critical for α-SMA expression in human lung myofibroblast, and the DNA methylation status at the CpG rich region of α-SMA is not a determinative factor for its inducible expression.

Keyphrases

binding protein
smooth muscle
dna methylation
poor prognosis
gene expression
genome wide
electronic health record
long non coding rna
extracellular matrix
data analysis
artificial intelligence