ESICM guidelines on acute respiratory distress syndrome: definition, phenotyping and respiratory support strategies.
Giacomo GrasselliCarolyn S CalfeeLuigi CamporotaDaniele PooleMarcelo B P AmatoMassimo AntonelliYaseen M ArabiFrancesca BaroncelliJeremy R BeitlerGiacomo BellaniGeoff BellinganBronagh BlackwoodLieuwe D J BosLaurent BrochardDaniel BrodieKaren E A BurnsAlain CombesSonia D'ArrigoDaniel De BackerAlexandre DemouleSharon EinavEddy FanNiall D FergusonJean-Pierre FratLuciano GattinoniClaude GuérinMargaret S HerridgeCarol HodgsonCatherine L HoughSamir JaberNicole P JuffermansChristian KaragiannidisJozef KeseciogluArthur KwizeraJohn G LaffeyJordi ManceboMichael A MatthayDaniel F McAuleyAlain MercatNuala J MeyerMarc MossLaveena MunshiSheila N MyatraMichelle Ng GongLaurent PapazianBhakti K PatelMariangela PellegriniAnders PernerAntonio PesentiLise PiquilloudHaibo QiuMarco V RanieriElisabeth RivielloArthur S SlutskyRenee D StapletonCharlotte SummersTaylor B ThompsonCarmen S Valente BarbasJesús VillarLorraine B WareBjörn WeissFernando G ZampieriElie AzoulayMaurizio Cecconinull nullPublished in: Intensive care medicine (2023)
The aim of these guidelines is to update the 2017 clinical practice guideline (CPG) of the European Society of Intensive Care Medicine (ESICM). The scope of this CPG is limited to adult patients and to non-pharmacological respiratory support strategies across different aspects of acute respiratory distress syndrome (ARDS), including ARDS due to coronavirus disease 2019 (COVID-19). These guidelines were formulated by an international panel of clinical experts, one methodologist and patients' representatives on behalf of the ESICM. The review was conducted in compliance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement recommendations. We followed the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach to assess the certainty of evidence and grade recommendations and the quality of reporting of each study based on the EQUATOR (Enhancing the QUAlity and Transparency Of health Research) network guidelines. The CPG addressed 21 questions and formulates 21 recommendations on the following domains: (1) definition; (2) phenotyping, and respiratory support strategies including (3) high-flow nasal cannula oxygen (HFNO); (4) non-invasive ventilation (NIV); (5) tidal volume setting; (6) positive end-expiratory pressure (PEEP) and recruitment maneuvers (RM); (7) prone positioning; (8) neuromuscular blockade, and (9) extracorporeal life support (ECLS). In addition, the CPG includes expert opinion on clinical practice and identifies the areas of future research.
Keyphrases
- clinical practice
- acute respiratory distress syndrome
- mechanical ventilation
- extracorporeal membrane oxygenation
- coronavirus disease
- meta analyses
- dna methylation
- respiratory failure
- systematic review
- end stage renal disease
- genome wide
- sars cov
- newly diagnosed
- high throughput
- chronic kidney disease
- adverse drug
- respiratory tract
- gene expression
- randomized controlled trial
- respiratory syndrome coronavirus
- prognostic factors
- quality improvement