Heterologous expression of cytotoxic sesquiterpenoids from the medicinal mushroom Lignosus rhinocerotis in yeast.

Hui-Yeng Yeannie YapMariano Jordi Muria-GonzalezBoon-Hong KongKeith A StubbsChon-Seng TanSzu-Ting NgNget-Hong TanPeter S SolomonShin-Yee FungYit Heng Chooi

Published in: Microbial cell factories (2017)

This demonstrates that yeast-based genome mining, guided by transcriptomics, is a promising approach for uncovering bioactive compounds from medicinal mushrooms.

Keyphrases

saccharomyces cerevisiae
poor prognosis
single cell
cell wall
binding protein
long non coding rna