Transcutaneous Retrobulbar Amphotericin B Injection for Invasive Fungal Sinusitis with Orbital Involvement: A Systematic Review.
Hasan AbdulbakiJacquelyn K CallanderJudd H FastenbergMatthew S RussellM Reza VagefiRobert C KerstenPatricia A LoftusPublished in: American journal of rhinology & allergy (2024)
TRAMB is an effective adjunctive treatment in IFS with mild-to-moderate orbital involvement when used in combination with standard of care debridement, systemic antifungal therapy, and immunosuppression reversal. Prospective longitudinal studies and multi-institutional randomized trials are necessary to determine the definitive utility of TRAMB.