Evidence for long noncoding RNA GAS5 up-regulationin patients with Klinefelter syndrome.

Michele SalemiRossella CannarellaRosita A CondorelliLaura CiminoFederico RidolfoGiorgio GiuratoCorrado RomanoSandro La VigneraAldo E Calogero

Published in: BMC medical genetics (2019)

These findings showed the occurrence of lncRNA GAS5 over-expression in KS patients. Whether this lncRNA is involved in the pathogenesis of inflammation and autoimmune diseases, atherogenesis or germ cell depletion in KS patients is not known. Further studies are needed.

Keyphrases

long noncoding rna
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
poor prognosis
risk assessment
long non coding rna
room temperature
case report