Identifying mismatch repair-deficient colon cancer: near-perfect concordance between immunohistochemistry and microsatellite instability testing in a large, population-based series.
Maurice B LoughreyJason McGrathHelen G ColemanPeter BankheadPerry MaxwellClaire McGreadyVictoria BinghamMatthew Phillip HumphriesStephanie G CraigStephen McQuaidManuel Salto-TellezJacqueline A JamesPublished in: Histopathology (2020)
MSI PCR testing and MMR IHC can be considered to be equally proficient tests for establishing MMR/MSI status, when there is awareness of the potential pitfalls of either method. The choice of methodology may depend on available services and expertise.