Exosomes from Human Umbilical Cord Mesenchymal Stem Cells Reduce Damage from Oxidative Stress and the Epithelial-Mesenchymal Transition in Renal Epithelial Cells Exposed to Oxalate and Calcium Oxalate Monohydrate.
Dian LiDan ZhangBo TangYue ZhouWenhao GuoQing KangZhang WangLianju ShenGuanghui WeiDawei HePublished in: Stem cells international (2019)
Exosomes from hUC-MSCs alleviate the oxidative injury and the epithelial-mesenchymal transformation of HK-2 cells that is induced by oxalate+COM.
Keyphrases
- mesenchymal stem cells
- umbilical cord
- oxidative stress
- induced apoptosis
- epithelial mesenchymal transition
- bone marrow
- endothelial cells
- signaling pathway
- cell therapy
- cell cycle arrest
- stem cells
- endoplasmic reticulum stress
- transforming growth factor
- dna damage
- ischemia reperfusion injury
- induced pluripotent stem cells
- diabetic rats
- high glucose
- pluripotent stem cells
- cell proliferation
- pi k akt