Nationwide Trends of Invasive Pneumococcal Disease in Spain From 2009 Through 2019 in Children and Adults During the Pneumococcal Conjugate Vaccine Era.
Sara de MiguelMirian DomenechFernando González-CamachoJulio SempereDolores ViciosoJuan Carlos SanzLuis García ComasCarmen ArdanuyAsunción FenollJose YustePublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2022)
Use of PCV13 in children has affected the epidemiology, reducing the burden of IPD in children but also in adults by herd protection; however, the increase in serotype 8 in adults is worrisome. Vaccination with PCV13 in adults seems to control IPD cases by PCV13 serotypes including serotype 3.