Prognostic impacts of tumoral expression and serum levels of PD-L1 and CTLA-4 in colorectal cancer patients.

Yusuke OmuraYuji ToiyamaYoshinaga OkugawaChengzeng YinTsunehiko ShigemoriKurando KusunokiYukina KusunokiShozo IdeTadanobu ShimuraHiroyuki FujikawaHiromi YasudaJunichiro HiroMasaki OhiMasato Kusunoki

Published in: Cancer immunology, immunotherapy : CII (2020)

We verified the prognostic impacts of mPD-L1, mCTLA-4, sPD-L1 and sCTLA-4 in pStage I-III CRC patients. Dual evaluation of immune checkpoint molecules in primary tissues or preoperative serum could identify a patient population with poor prognosis in these patients.

Keyphrases

poor prognosis
end stage renal disease
newly diagnosed
ejection fraction
long non coding rna
gene expression
case report