Login / Signup

Identifying Aging and Alzheimer Disease-Associated Somatic Variations in Excitatory Neurons From the Human Frontal Cortex.

Meng ZhangGerard A BoulandHenne HolstegeMarcel J T Reinders
Published in: Neurology. Genetics (2023)
Our results show that combining scRNA-seq and WGS data can successfully detect putative somatic mutations. The putative somatic mutations detected from ROSMAP data set have provided new insights into the association of AD and aging with brain somatic mutagenesis.
Keyphrases