The Osteoarthritis Thumb Therapy (OTTER) II Trial: a study protocol for a three-arm multi-centre randomised placebo controlled trial of the clinical effectiveness and efficacy and cost-effectiveness of splints for symptomatic thumb base osteoarthritis.

Jo AdamsPaula BarrattNigel K ArdenSofia Barbosa BouçasSarah BradleyMichael DohertySusan DuttonKrysia DziedzicRachael Gooberman-HillKelly Hislop LennieCorinne Hutt GreenyerVictoria JansenRamon Luengo-FernandezClaire MeagherPeter WhiteMark A Williams

Published in: BMJ open (2019)

ISRCTN54744256.

Keyphrases

study protocol
double blind
clinical trial
randomized controlled trial
rheumatoid arthritis
phase iii
open label
knee osteoarthritis
phase ii
placebo controlled
bone marrow