Rationale and Design of the COVID-19 Outpatient Prevention Evaluation (COPE - Coalition V) Randomized Clinical Trial: Hydroxychloroquine vs. Placebo in Non-Hospitalized Patients.

Haliton Alves de Oliveira JúniorCleusa P FerriIcaro BoszczowskiGustavo Bernardes de Figueiredo OliveiraAlexandre B CavalcantiRegis G RosaRenato D LopesLuciano C P AzevedoViviane C VeigaOtavio BerwangerÁlvaro Avezum

Published in: Arquivos brasileiros de cardiologia (2022)

This study has the potential to reliably answer the scientific question of HCQ use in outpatients with COVID-19. To our knowledge, this is the largest trial evaluating HCQ in non-hospitalized individuals with COVID-19.

Keyphrases

coronavirus disease
sars cov
phase iii
healthcare
respiratory syndrome coronavirus
clinical trial
randomized controlled trial
risk assessment
phase ii
open label