Phosphodiesterase 4 D (PDE4D) gene polymorphisms and risk of ischemic stroke: A systematic review and meta-analysis.

Manabesh NathPriyanka SwarnkarShubham MisraKameshwar Prasad

Published in: Acta neurologica Belgica (2023)

Findings of this meta-analysis conclude that SNP45, SNP83, and SNP89 polymorphism could be capable of increasing stroke susceptibility in Asians but not in the Caucasian population. Genotyping of SNP 45, 83, 89 polymorphisms may be used as a predictor for the occurrence of IS.

Keyphrases

genome wide
systematic review
high density
dna methylation
genetic diversity
atrial fibrillation
risk assessment
gene expression
randomized controlled trial
meta analyses
african american
blood brain barrier
cerebral ischemia