Current management of adults receiving oral anti-cancer medications: A scoping review protocol.

Oncology has been undergoing a profound transition in the last ten years or more with the increase in oral anti-cancer medications. Approximately 25% of all anti-cancer medication is now designed for oral use and this is likely to increase prospectively. These treatments are convenient for patients and are often preferred by them, yet there are similar safely and toxicity concerns as there are to intravenous treatment. Oral anti-cancer medications (OAMs) have the potential to alleviate capacity issues in cancer treating units as patients receive their treatment at home, however there remains a requirement for safe and efficient assessment and care. Consequently, the management of patients on oral anti-cancer is of paramount importance but as to the location of such patient assessment and monitoring and by which health care professional is subject to ongoing debate.  This paper presents a protocol for a scoping review which aims to systematically and comprehensively map the available literature on the current management of adults receiving oral anti-cancer medications. The scoping review will follow the published guidance to direct the various steps involved. The report will be guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews (PRISMA-ScR) framework to ensure methodological and reporting quality.  The review will be performed by two reviewers and checked by a third reviewer and will be iterative in the process. This scoping review will provide a narrative synthesis and map the extent of available literature on the management of individuals receiving oral anti-cancer medication. This work is an appropriate initial stage in presenting the literature to inform the subsequent steps in a multi-phased research study which aims to establish and analyse the safety and efficacy of an integrated care model for the management of patients receiving OAM in the community by an advanced nurse.