The effects of prednisolone treatment on serological responses and lipid profiles in Ethiopian leprosy patients with Erythema Nodosum Leprosum reactions.

Diana N J Lockwood Melaku TilahunKidist BoboshaSaba M LambertStephen L WalkerJohn S SpencerAbraham AseffaHazel M DockrellDiana N Lockwood

Published in: PLoS neglected tropical diseases (2018)

The significantly increased prednisolone-induced LDL and TG levels, particularly in patients with chronic ENL reactions, is a concern in the use of prednisolone for extended periods in ENL patients. The findings highlight the importance of monitoring lipid profiles during treatment of patients to minimize the long-term risk of prednisolone-induced complications.

Keyphrases

high glucose
diabetic rats
end stage renal disease
newly diagnosed
ejection fraction
fatty acid
oxidative stress
risk factors
patient reported