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Phase I study of ribociclib and everolimus in children with newly diagnosed DIPG and high-grade glioma: A CONNECT pediatric neuro-oncology consortium report.

Mariko DeWireMargot A LazowOlivia CampagneJames LeachChristine FullerShiva Senthil KumarJoseph StanekPeter de BlankTrent R HummelNatasha Pillay-SmileyRalph SalloumCharles B StevensonPatricia BaxterDavid GassStewart GoldmanSarah E S LearyAdam CarleLeonie MikaelDorothy CrabtreeBrooklyn ChaneyAdam LaneRachid DrissiClinton F StewartMaryam Fouladi
Published in: Neuro-oncology advances (2022)
. Results will inform a molecularly guided phase II study underway to evaluate efficacy.
Keyphrases
  • phase ii study
  • high grade
  • newly diagnosed
  • open label
  • locally advanced
  • palliative care
  • young adults
  • low grade
  • randomized controlled trial
  • radiation therapy
  • placebo controlled