Neutrophil to lymphocyte ratio as a predictive biomarker for computed tomography scan use in mild traumatic brain injury.
Georgios A AlexiouGeorgios D LianosAggeliki TzimaAthanasios SotiropoulosAnastasios NasiosDimitris MetaxasAndreas ZigourisJolanda Zika RnMichail MitsisSpyridon VoulgarisPublished in: Biomarkers in medicine (2021)
Aim: Traumatic brain injury (TBI) is a serious health concern. We set out to investigate the role of neutrophil-to-lymphocytes ratio (NLR) at admission for predicting the need for computed tomography (CT) in mild-TBI. Materials & methods: A retrospective study of adult patients who presented with mild-TBI Results: One hundred and thirty patients met the inclusion criteria. Seventy-four patients had positive CT-findings. The mean NLR-levels at presentations were 5.6 ± 4.8. Patients with positive CT-findings had significant higher NLR-levels. Receiver operating characteristic curve analysis was conducted and the threshold of NLR-levels for detecting the cases with positive CT-findings was 2.5, with 78.1% sensitivity and 63% specificity Conclusion: To the best of our knowledge no previous study has assessed the value of NLR-levels for predicting the need for CT in mild-TBI.
Keyphrases
- computed tomography
- traumatic brain injury
- dual energy
- image quality
- mild traumatic brain injury
- contrast enhanced
- positron emission tomography
- end stage renal disease
- newly diagnosed
- magnetic resonance imaging
- ejection fraction
- healthcare
- severe traumatic brain injury
- peritoneal dialysis
- emergency department
- magnetic resonance
- prognostic factors
- young adults
- mental health
- peripheral blood
- risk assessment
- pet ct
- health promotion