Management of patients with early-stage ovarian clear cell carcinoma: risk stratification and fertility conservation.
Beryl L Manning-GeistSushmita GordhandasAnjelica HodgsonQin C ZhouAlexia IasonosDennis S ChiLora EllensonCarol A AghajanianNadeem R Abu-RustumMario L LeitaoKara LongMaria M RubinsteinYukio SonodaKaled AlektiarBritta WeigeltOliver ZivanovicRachel N GrishamPublished in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society (2022)
In patients with completely staged ovarian clear cell carcinoma, those with stage IA/IC1 disease have an excellent prognosis, regardless of chemotherapy. Aberrant p53 expression may portend worse outcomes. Additional investigation is warranted on the safety of fertility conservation in patients with stage IA/IC1 disease.