The CD2-CD58 axis: A novel marker predicting poor prognosis in patients with low-grade gliomas and potential therapeutic approaches.

Mingwei WuYiyuan ChenHua GaoLiu Chunhui

Published in: Immunity, inflammation and disease (2023)

Overall, our findings highlight the significant association between the CD2-CD58 axis and poor survival in LGG patients. High CD58 expression is implicated in T cell-mediated immune responses as an immunosuppressive factor and affect inhibitory immune checkpoint genes.

Keyphrases

peritoneal dialysis
end stage renal disease
poor prognosis
low grade
high grade
long non coding rna
immune response
genome wide
dendritic cells
toll like receptor
ejection fraction
binding protein
newly diagnosed
inflammatory response
free survival
bioinformatics analysis