Predictive potential of various plasma inflammation-, angiogenesis-, and extracellular matrix remodeling-associated mediators for intra-amniotic inflammation and/or microbial invasion of the amniotic cavity in preterm labor.

Eunwook JooSubeen HongKyo Hoon ParkHyeon Ji KimMin Jung LeeSue Shin

Published in: Archives of gynecology and obstetrics (2024)

IGFBP-2, LBP, MMP-2, MMP-8, and S100A8/A9 may represent valuable plasma biomarkers for predicting IAI/MIAC in women with PTL. Combination of LBP, MMP-2, and MMP-8 expression data can significantly improve the predictive potential for IAI/MIAC.

Keyphrases

cell migration
extracellular matrix
oxidative stress
poor prognosis
endothelial cells
microbial community
human health
electronic health record
preterm birth
risk assessment
bone marrow
mesenchymal stem cells
big data
preterm infants
climate change
artificial intelligence