Weight loss normalizes enhanced expression of the oncogene survivin in visceral adipose tissue and blood leukocytes from individuals with obesity.

Andrea G IzquierdoMarcos C CarreiraGemma Rodriguez-CarneroAlfredo Fernandez-QuintelaAurelio M SueiroMiguel A Martinez-OlmosGerman GuzmanDaniel-Antonio de Luis RomanMarcela A S PinhelCarolina F NicolettiCarla B NoninoFrancisco J OrtegaMaria P PortilloJose M Fernandez-RealFelipe F CasanuevaAna Belén Crujeiras

Published in: International journal of obesity (2005) (2020)

Weight loss is effective in decreasing survivin levels. Also, PBL/PBMC should be regarded as appropriate mirror of survivin levels in VAT for the identification of an obesity-related protumoral microenvironment.

Keyphrases

weight loss
bariatric surgery
insulin resistance
adipose tissue
roux en y gastric bypass
gastric bypass
poor prognosis
weight gain
stem cells
metabolic syndrome
glycemic control
high fat diet
high fat diet induced
obese patients
type diabetes
skeletal muscle
binding protein
bioinformatics analysis