Accumulation of Paneth Cells in Early Colorectal Adenomas Is Associated with Beta-Catenin Signaling and Poor Patient Prognosis.

Erika López-ArribillagaBing YanTeresa Lobo-JarneYolanda Guillén Silvia MenéndezMontserrat AndreuAnna BigasMar IglesiasLluís Espinosa

Published in: Cells (2021)

Our results indicate that Paneth cells contribute to the initial steps of cancer progression by providing the stem cell niche to adenoma cells, which could be therapeutically exploited.

Keyphrases

pi k akt
cell cycle arrest
signaling pathway
induced apoptosis
stem cells
endoplasmic reticulum stress
young adults
papillary thyroid