Anna Bigas

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 32

Top Venues

Nature communications

EMBO molecular medicine

Science advances

The EMBO journal

Centro de Investigación Biomédica en Red de Cáncer

University of Barcelona (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Centro de Investigación Biomédica en Red de Cáncer Mar 26 2020

Spain

SCIENTIFIC DIRECTOR

Institut Hospital del Mar d'Investigacions Mèdiques Jan 15 2009

Spain

Group Leader :: Programme of Cancer Research

Institut d'Investigacio Biomedica de Bellvitge Jan 01 1997 - Jan 15 2009

Spain

Group Leader :: Molecular Oncology

Fred Hutchinson Cancer Research Center Jan 01 1993 - Mar 31 1997

United States

Post-doctoral researcher

Education History

University of Barcelona Jan 01 1989 - Jan 01 1993

Spain

PHD :: Cell Biology

Publications

Roshana Thambyrajah, Maria Maqueda, Wen Hao Neo, Kathleen Imbach, Yolanda Guillén, Daniela Grases, Zaki Fadlullah, Stefano Gambera, Francesca Matteini, Xiaonan Wang, Fernando J Calero-Nieto, Manel Esteller, Maria Carolina Florian, Eduard Porta, Rui Benedito, Berthold Göttgens, Georges Lacaud, Lluís Espinosa, Anna Bigas
Cis inhibition of NOTCH1 through JAGGED1 sustains embryonic hematopoietic stem cell fate. Nature communications 15 (1) (2024)
Michael Boutros, Michael Baumann, Anna Bigas, Linda Chaabane, Julien Guerin, Jens K Habermann, Aurélien Jobard, Pier Giuseppe Pelicci, Oliver Stegle, Giovanni Tonon, Alfonso Valencia, Eva C Winkler, Patricia Blanc, Ruggero De Maria, René H Medema, Peter Nagy, Josep Tabernero, Eric Solary
UNCAN.eu: Toward a European Federated Cancer Research Data Hub. Cancer discovery 14 (1) (2024)
Roshana Thambyrajah, Maria Maqueda, Muhammad Zaki Hidayatullah Fadlullah, Martin Proffitt, Wen Hao Neo, Yolanda Guillén, Marta Casado-Pelaez, Patricia Herrero-Molinero, Carla Brujas, Noemi Castelluccio, Jessica González, Arnau Iglesias, Laura Marruecos, Cristina Ruiz-Herguido, Manel Esteller, Elisabetta Mereu, Georges Lacaud, Lluís Espinosa, Anna Bigas
IκBα controls dormancy in hematopoietic stem cells via retinoic acid during embryonic development. Nature communications 15 (1) (2024)
Roshana Thambyrajah, Maria Maqueda, Muhammad Zaki Hidayatullah Fadlullah, Martin Proffitt, Wen Hao Neo, Yolanda Guillén, Marta Casado-Pelaez, Patricia Herrero-Molinero, Carla Brujas, Noemi Castelluccio, Jessica González, Arnau Iglesias, Laura Marruecos, Cristina Ruiz-Herguido, Manel Esteller, Elisabetta Mereu, Georges Lacaud, Lluís Espinosa, Anna Bigas
IκBα controls dormancy in hematopoietic stem cells via retinoic acid during embryonic development. Nature communications 15 (1) (2024)
Roshana Thambyrajah, Maria Maqueda, Muhammad Zaki Hidayatullah Fadlullah, Martin Proffitt, Wen Hao Neo, Yolanda Guillén, Marta Casado-Pelaez, Patricia Herrero-Molinero, Carla Brujas, Noemi Castelluccio, Jessica González, Arnau Iglesias, Laura Marruecos, Cristina Ruiz-Herguido, Manel Esteller, Elisabetta Mereu, Georges Lacaud, Lluís Espinosa, Anna Bigas
IκBα controls dormancy in hematopoietic stem cells via retinoic acid during embryonic development. Nature communications 15 (1) (2024)
Roshana Thambyrajah, Maria Maqueda, Wen Hao Neo, Kathleen Imbach, Yolanda Guillén, Daniela Grases, Zaki Fadlullah, Stefano Gambera, Francesca Matteini, Xiaonan Wang, Fernando J Calero-Nieto, Manel Esteller, Maria Carolina Florian, Eduard Porta, Rui Benedito, Berthold Göttgens, Georges Lacaud, Lluís Espinosa, Anna Bigas
Cis inhibition of NOTCH1 through JAGGED1 sustains embryonic hematopoietic stem cell fate. Nature communications 15 (1) (2024)
Michael Boutros, Michael Baumann, Anna Bigas, Linda Chaabane, Julien Guerin, Jens K Habermann, Aurélien Jobard, Pier Giuseppe Pelicci, Oliver Stegle, Giovanni Tonon, Alfonso Valencia, Eva C Winkler, Patricia Blanc, Ruggero De Maria, René H Medema, Peter Nagy, Josep Tabernero, Eric Solary
UNCAN.eu: Toward a European Federated Cancer Research Data Hub. Cancer discovery 14 (1) (2024)
Mercedes Barrero, Aleksey Lazarenkov, Enrique Blanco, Luís G Palma, Anna V López-Rubio, Moritz Bauer, Anna Bigas, Luciano Di Croce, José Luis Sardina, Bernhard Payer
The interferon γ pathway enhances pluripotency and X-chromosome reactivation in iPSC reprogramming. Science advances 10 (32) (2024)
Roshana Thambyrajah, Maria Maqueda, Wen Hao Neo, Kathleen Imbach, Yolanda Guillén, Daniela Grases, Zaki Fadlullah, Stefano Gambera, Francesca Matteini, Xiaonan Wang, Fernando J Calero-Nieto, Manel Esteller, Maria Carolina Florian, Eduard Porta, Rui Benedito, Berthold Göttgens, Georges Lacaud, Lluís Espinosa, Anna Bigas
Cis inhibition of NOTCH1 through JAGGED1 sustains embryonic hematopoietic stem cell fate. Nature communications 15 (1) (2024)
Mercedes Barrero, Aleksey Lazarenkov, Enrique Blanco, Luís G Palma, Anna V López-Rubio, Moritz Bauer, Anna Bigas, Luciano Di Croce, José Luis Sardina, Bernhard Payer
The interferon γ pathway enhances pluripotency and X-chromosome reactivation in iPSC reprogramming. Science advances 10 (32) (2024)
Roshana Thambyrajah, Maria Maqueda, Muhammad Zaki Hidayatullah Fadlullah, Martin Proffitt, Wen Hao Neo, Yolanda Guillén, Marta Casado-Pelaez, Patricia Herrero-Molinero, Carla Brujas, Noemi Castelluccio, Jessica González, Arnau Iglesias, Laura Marruecos, Cristina Ruiz-Herguido, Manel Esteller, Elisabetta Mereu, Georges Lacaud, Lluís Espinosa, Anna Bigas
IκBα controls dormancy in hematopoietic stem cells via retinoic acid during embryonic development. Nature communications 15 (1) (2024)
Violeta García-Hernández, David Arambilet, Yolanda Guillén, Teresa Lobo-Jarne, Maria Maqueda, Christos Gekas, Jessica González, Arnau Iglesias, Nerea Vega-García, Inés Sentís, Juan L Trincado, Ian Márquez-López, Holger Heyn, Mireia Camós, Lluís Espinosa, Anna Bigas
β-Catenin activity induces an RNA biosynthesis program promoting therapy resistance in T-cell acute lymphoblastic leukemia. EMBO molecular medicine (2023)
Violeta García-Hernández, David Arambilet, Yolanda Guillén, Teresa Lobo-Jarne, Maria Maqueda, Christos Gekas, Jessica González, Arnau Iglesias, Nerea Vega-García, Inés Sentís, Juan L Trincado, Ian Márquez-López, Holger Heyn, Mireia Camós, Lluís Espinosa, Anna Bigas
β-Catenin activity induces an RNA biosynthesis program promoting therapy resistance in T-cell acute lymphoblastic leukemia. EMBO molecular medicine 15 (2) (2023)
Irene Pecharromán, Laura Solé, Daniel Alvarez-Villanueva, Teresa Lobo-Jarne, Josune Alonso-Marañón, Joan Bertran, Yolanda Guillén, Ángela Montoto, María Martínez-Iniesta, Violeta García-Hernández, Gemma Giménez, Ramon Salazar, Cristina Santos, Marta Garrido, Eva Borràs, Eduard Sabidó, Ester Bonfill-Teixidor, Raffaella Iurlaro, Joan Seoane, Alberto Villanueva, Mar Iglesias, Anna Bigas, Lluís Espinosa
IκB kinase-α coordinates BRD4 and JAK/STAT signaling to subvert DNA damage-based anticancer therapy. The EMBO journal (2023)
Violeta García-Hernández, David Arambilet, Yolanda Guillén, Teresa Lobo-Jarne, Maria Maqueda, Christos Gekas, Jessica González, Arnau Iglesias, Nerea Vega-García, Inés Sentís, Juan L Trincado, Ian Márquez-López, Holger Heyn, Mireia Camós, Lluís Espinosa, Anna Bigas
β-Catenin activity induces an RNA biosynthesis program promoting therapy resistance in T-cell acute lymphoblastic leukemia. EMBO molecular medicine 15 (2) (2023)
Violeta García-Hernández, David Arambilet, Yolanda Guillén, Teresa Lobo-Jarne, Maria Maqueda, Christos Gekas, Jessica González, Arnau Iglesias, Nerea Vega-García, Inés Sentís, Juan L Trincado, Ian Márquez-López, Holger Heyn, Mireia Camós, Lluís Espinosa, Anna Bigas
β-Catenin activity induces an RNA biosynthesis program promoting therapy resistance in T-cell acute lymphoblastic leukemia. EMBO molecular medicine 15 (2) (2023)
Violeta García-Hernández, David Arambilet, Yolanda Guillén, Teresa Lobo-Jarne, Maria Maqueda, Christos Gekas, Jessica González, Arnau Iglesias, Nerea Vega-García, Inés Sentís, Juan L Trincado, Ian Márquez-López, Holger Heyn, Mireia Camós, Lluís Espinosa, Anna Bigas
β-Catenin activity induces an RNA biosynthesis program promoting therapy resistance in T-cell acute lymphoblastic leukemia. EMBO molecular medicine 15 (2) (2023)
Violeta García-Hernández, David Arambilet, Yolanda Guillén, Teresa Lobo-Jarne, Maria Maqueda, Christos Gekas, Jessica González, Arnau Iglesias, Nerea Vega-García, Inés Sentís, Juan L Trincado, Ian Márquez-López, Holger Heyn, Mireia Camós, Lluís Espinosa, Anna Bigas
β-Catenin activity induces an RNA biosynthesis program promoting therapy resistance in T-cell acute lymphoblastic leukemia. EMBO molecular medicine 15 (2) (2023)
Roshana Thambyrajah, Anna Bigas
Notch Signaling in HSC Emergence: When, Why and How. Cells 11 (3) (2022)
Laura Solé, Teresa Lobo-Jarne, Daniel Alvarez-Villanueva, Josune Alonso-Marañón, Yolanda Guillén, Marta Guix, Irene Sangrador, Catalina Rozalén, Anna Vert, Antonio Barbachano, Joan Lop, Marta Salido, Beatriz Bellosillo, Raquel García-Romero, Marta Garrido, Jessica González, María Martínez-Iniesta, Erika López-Arribillaga, Ramón Salazar, Clara Montagut, Ferràn Torres, Mar Iglesias, Toni Celià-Terrassa, Alberto Muñoz, Alberto Villanueva, Anna Bigas, Lluís Espinosa
p53 wild-type colorectal cancer cells that express a fetal gene signature are associated with metastasis and poor prognosis. Nature communications 13 (1) (2022)
Anna Bigas, Luis Galán Palma, Gayathri M Kartha, Alessandra Giorgetti
Using Pluripotent Stem Cells to Understand Normal and Leukemic Hematopoietic Development. Stem cells translational medicine 11 (11) (2022)
Lili Kotmayer, Damia Romero-Moya, Oskar Marin-Bejar, Emilia J Kozyra, Albert Català, Anna Bigas, Marcin W Wlodarski, Csaba Bödör, Alessandra Giorgetti
GATA2 deficiency and MDS/AML: Experimental strategies for disease modelling and future therapeutic prospects. British journal of haematology 199 (4) (2022)
Fernando Gallardo, Evelyn Andrades, Arnau Iglesias, Jessica González, Laura Solé, Yolanda Guillén, Gonzalo Blanco, Luis Colomo, Eva Gimeno, David Conde-Estévez, Eva Rodriguez, Isabel Bielsa-Marso, Mar Iglesias, Beatriz Bellosillo, Ramon M Pujol, Jose R Regueiro, Anna Bigas, Lluís Espinosa
Sézary syndrome patient-derived models allow drug selection for personalized therapy. Blood advances 6 (11) (2022)
Josune Alonso-Marañón, Alberto Villanueva, Josep Maria Piulats, María Martínez-Iniesta, Laura Solé, Juan Martín-Liberal, Sonia Segura, Ramon M Pujol, Mar Iglesias, Anna Bigas, Fernando Gallardo, Lluís Espinosa
Combination of chemotherapy with BRAF inhibitors results in effective eradication of malignant melanoma by preventing ATM-dependent DNA repair. Oncogene 40 (31) (2021)
Erika López-Arribillaga, Bing Yan, Teresa Lobo-Jarne, Yolanda Guillén, Silvia Menéndez, Montserrat Andreu, Anna Bigas, Mar Iglesias, Lluís Espinosa
Accumulation of Paneth Cells in Early Colorectal Adenomas Is Associated with Beta-Catenin Signaling and Poor Patient Prognosis. Cells 10 (11) (2021)
Laura Marruecos, Joan Bertran, Daniel Álvarez-Villanueva, María Carmen Mulero, Yolanda Guillén, Luís G Palma, Martin Floor, Anna Vert, Sara Arce-Gallego, Irene Pecharroman, Laura Batlle, Jordi Villà-Freixa, Gourisankar Ghosh, Anna Bigas, Lluís Espinosa
Dynamic chromatin association of IκBα is regulated by acetylation and cleavage of histone H4. EMBO reports 22 (8) (2021)
Miguel Alejandro Galindo-Campos, Nura Lutfi, Sarah Bonnin, Carlos Manuel Martínez, Talía Velasco-Hernandez, Violeta García-Hernández, Juan Martin-Caballero, Coral Ampurdanés, Ramón Gimeno, Lluis Colomo, Gael Roue, Guillaume Guilbaud, Françoise Dantzer, Pilar Navarro, Matilde Murga, Oscar Fernandez-Capetillo, Anna Bigas, Pablo Menendez, Julian Sale, José Yélamos
Distinct roles for PARP-1 and PARP-2 in c-Myc-driven B-cell lymphoma in mice. Blood (2021)
Laura Marruecos, Joan Bertran, Yolanda Guillén, Jéssica González, Raquel Batlle, Erika López-Arribillaga, Marta Garrido, Cristina Ruiz-Herguido, Dominique Lisiero, Mónica González-Farré, Sara Arce-Gallego, Mar Iglesias, Angel R Nebreda, Shigeki Miyamoto, Anna Bigas, Lluís Espinosa
IκBα deficiency imposes a fetal phenotype to intestinal stem cells. EMBO reports 21 (6) (2020)
Pedro Vizán, Arantxa Gutiérrez, Isabel Espejo, Marc García-Montolio, Martin Lange, Ana Carretero, Atefeh Lafzi, Luisa de Andrés-Aguayo, Enrique Blanco, Roshana Thambyrajah, Thomas Graf, Holger Heyn, Anna Bigas, Luciano Di Croce
The Polycomb-associated factor PHF19 controls hematopoietic stem cell state and differentiation. Science advances 6 (32) (2020)
Cristina Porcheri, Ohad Golan, Fernando J Calero-Nieto, Roshana Thambyrajah, Cristina Ruiz-Herguido, Xiaonan Wang, Francesca Catto, Yolanda Guillén, Roshani Sinha, Jessica González, Sarah J Kinston, Samanta A Mariani, Antonio Maglitto, Chris S Vink, Elaine Dzierzak, Pierre Charbord, Berthold Göttgens, Lluís Espinosa, David Sprinzak, Anna Bigas
Notch ligand Dll4 impairs cell recruitment to aortic clusters and limits blood stem cell generation. The EMBO journal 39 (8) (2020)
Anna Bigas, Yolanda Guillén, Leonie Schoch, David Arambilet
Revisiting β-Catenin Signaling in T-Cell Development and T-Cell Acute Lymphoblastic Leukemia. BioEssays : news and reviews in molecular, cellular and developmental biology 42 (2) (2019)
Anna Bigas, Claudia Waskow
Blood stem cells: from beginning to end. Development (Cambridge, England) 143 (19) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Anna Bigas