High P4HA1 expression is an independent prognostic factor for poor overall survival and recurrent-free survival in head and neck squamous cell carcinoma.

Qun LiZhisen ShenZhenhua WuYi ShenHongxia DengChong-Chang ZhouHuigao Liu

Published in: Journal of clinical laboratory analysis (2019)

This integrated analysis provides strong evidence that increasing P4HA1 expression is significantly associated with the carcinogenesis of HNSCC. Additionally, high P4HA1 expression serves as both diagnostic biomarker and independent prognostic factor for poor OS and RFS in HNSCC patients.

Keyphrases

prognostic factors
poor prognosis
free survival
end stage renal disease
binding protein
chronic kidney disease
ejection fraction
long non coding rna
peritoneal dialysis
hyaluronic acid