Aberrant DNA methylation results in altered gene expression in non-alcoholic steatohepatitis-related hepatocellular carcinomas.
Ying TianEri AraiSatomi MakiuchiNoboru TsudaJunko KuramotoKentaro OharaYoriko TakahashiNanako ItoHidenori OjimaNobuyoshi HiraokaMasahiro GotohTeruhiko YoshidaYae KanaiPublished in: Journal of cancer research and clinical oncology (2020)
DNA methylation alterations may occur under the necroinflammatory conditions characteristic of NASH and participate in NASH-related hepatocarcinogenesis through aberrant expression of tumor-related genes.