Can angiotropism and lymphovascular invasion refine the current cutaneous melanoma staging system?
Patricia NamubiruWilliam DalleywaterShaimaa Elsaid LashinSomaia ElsheikhPublished in: Journal of cutaneous pathology (2023)
AT is a marker for angiotropic extravascular migratory tumor spread (angiotropic EVMM), and LVI is a marker for intra-lymphovascular tumor spread. Both predict poor prognosis. Given its ease of detection, AT could be adopted as a histologpathological feature in the routine assessment of primary cutaneous malignant melanoma cases.