Anti-osteoporosis activity of casticin in ovariectomized rats.
Dong ZhangJianmin LiXuejia LiWanxin LiuYing YuHao SunJiajun WuZhichao GeKai LvYanting ShaoShuqiang WangXiaojian YePublished in: Toxicology research (2024)
Casticin improved bone density, bone biomechanics, the level of calcium and estrogen, the release of pro-inflammatory factor and oxidative stress to alleviate osteoporosis, which was associated with the upregulation of Nrf2/HO-1 pathway.