Synergism Through WEE1 and CHK1 Inhibition in Acute Lymphoblastic Leukemia.
Andrea Ghelli Luserna Di RoràMatteo BocconcelliAnna FerrariCarolina TerragnaSamantha BrunoEnrica ImbrognoNeil BeeharryValentina RobustelliMartina GhettiRoberta NapolitanoGabriella ChirumboloGiovanni MarconiCristina PapayannidisStefania PaoliniChiara SartorFrancesco LanzaTimothy J YenGiovanni MartinelliPublished in: Cancers (2019)
Our findings suggest that the combination of CHK1 and WEE1 inhibitors may be a promising therapeutic strategy to be tested in clinical trials for adult ALL.