Efficacy and safety of hangeshashinto for treatment of GERD refractory to proton pump inhibitors : Usual dose proton pump inhibitors plus hangeshashinto versus double-dose proton pump inhibitors: randomized, multicenter open label exploratory study.
Toshihisa TakeuchiHitoshi HongoTsuguhiro KimuraYuichi KojimaSatoshi HaradaKazuhiro OtaNozomi TakeuchiTakao NoguchiTakuya InoueMitsuyuki MuranoKazuhide HiguchiPublished in: Journal of gastroenterology (2019)
HST may be beneficial for patients with PPI-refractory GERD, particularly in non-obese and non-elderly patients with dyspepsia symptoms.
Keyphrases
- open label
- gastroesophageal reflux disease
- double blind
- phase iii
- phase ii
- clinical trial
- adipose tissue
- phase ii study
- metabolic syndrome
- type diabetes
- middle aged
- randomized controlled trial
- squamous cell carcinoma
- helicobacter pylori infection
- bariatric surgery
- physical activity
- radiation therapy
- obese patients
- irritable bowel syndrome