Switch from Tenofovir Disoproxil Fumarate to Tenofovir Alafenamide in People Living with HIV: Lipid Changes and Statin Underutilization.
Laurence BrunetPatrick W G MallonJennifer S FuscoMichael B WohlfeilerGirish PrajapatiAndrew BeyerGregory P FuscoPublished in: Clinical drug investigation (2021)
In this large, diverse population of PLWH in the USA, the switch from TDF to TAF was associated with development of less favorable lipid profiles, regardless of pharmaco-enhancers or third-agent use. Statins remained underutilized after a switch from TDF to TAF.