Impact of weight loss on treatment with PD-1/PD-L1 inhibitors plus chemotherapy in advanced non-small-cell lung cancer.

Taichi MiyawakiTateaki NaitoMichitoshi YabeHiroaki KodamaNaoya NishiokaEriko MiyawakiNobuaki MamesayaHaruki KobayashiShota OmoriKazushige WakudaAkira OnoHirotsugu KenmotsuHaruyasu MurakamiKeita MoriHideyuki HaradaKazuhisa TakahashiToshiaki Takahashi

Published in: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (2021)

Pre-treatment weight loss may reduce treatment efficacy and shorten survival time in patients receiving PD-1/PD-L1 inhibitors plus chemotherapy. Early evaluation and intervention for weight loss might improve oncological outcomes in patients with advanced NSCLC.

Keyphrases

weight loss
advanced non small cell lung cancer
bariatric surgery
randomized controlled trial
small cell lung cancer
type diabetes
prostate cancer
epidermal growth factor receptor
adipose tissue
rectal cancer
radical prostatectomy
smoking cessation