Association between anticholinergic (atropinic) drug exposure and cognitive function in longitudinal studies among individuals over 50 years old: a systematic review.

Laurine AndreAdeline GalliniFrançois MontastrucJean-Louis MontastrucAntoine PiauMaryse Lapeyre-MestreVirginie Gardette

Published in: European journal of clinical pharmacology (2019)

Our review suggests a deleterious effect of anticholinergic exposure on mid/long-term cognitive function but should be confirmed in studies with improved methodology. Meanwhile, prescription of anticholinergic drugs should remain cautious.

Keyphrases

case control
cross sectional
emergency department
drug induced